HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-[2-[2-Ethyl-4-oxo-3,4-dihydro-3-quinazolinyl]ethoxy]nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(2-Bromoethoxy)-4-nitrobenzene | HCID 235987 | — |
| Reactant | 2-Ethylquinazolin-4(1H)-one | HCID 135444528 | — |
| Product | 4-[2-[2-Ethyl-4-oxo-3,4-dihydro-3-quinazolinyl]ethoxy]nitrobenzene | HCID 21960203 | 64.4% |
Reaction Steps
The title compound (1.246 g, 64%) was prepared from 2-ethyl-4-oxo-3,4-dihyroquinazoline (1.0 g, 5.7 mmol) and 4-[2-bromoethoxy]nitrobenzene (1.696 g, 6.8 mmol) and K2CO3 (1.58 g, 11.49 mmol) as a base by a similar procedure to that described in preparation 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310069B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-ca401ddbf35744739809efb4d7610532 |
| Source note | uspto-grants-2001_10 |