HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-[2-[2-Methyl-4-oxo-3,4-dihydro-3-quinazolinyl]ethoxy]nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(2-Bromoethoxy)-4-nitrobenzene | HCID 235987 | — |
| Reactant | 2-Methyl-4(3H)-quinazolinone | HCID 135400457 | — |
| Product | 4-[2-[2-Methyl-4-oxo-3,4-dihydro-3-quinazolinyl]ethoxy]nitrobenzene | HCID 21960146 | 60% |
Reaction Steps
The title compound (1.2 g, 60%) was prepared from 2-methyl-4-oxo-3,4-dihydroquinazoline (1.0 g, 6.25 mmol) and 4-[2-bromoethoxy]nitrobenzene (1.69 g, 6.9 mmol) and K2CO3 (1.73 g, 12.5 mmol) as a base by a similar procedure to that described in preparation 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310069B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-720106353dac4fb4b3a1ff7c8e8535b1 |
| Source note | uspto-grants-2001_10 |