(R)-beta-aminophenethyl alcohol → HCID 53653707, compound

HRID 382298Notes

Reaction equation

HRID 382298 reaction equation
[CH:1]1[CH:6]=[CH:5][C:4]([C@@H:7]([NH2:10])[CH2:8][OH:9])=[CH:3][CH:2]=1.Cl[CH2:12]/[CH:13]=[CH:14]\[CH2:15]Cl>>[C:4]1([C@@H:7]([N:10]2[CH2:15][CH:14]=[CH:13][CH2:12]2)[CH2:8][OH:9])[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=1

Participants

3

Reactant 2

HCID 2724025(R)-beta-aminophenethyl alcoholHCID 64321151,4-Dichloro-cis-2-butene

Product 1

HCID 53653707HCID 53653707, compoundYield 58%

Procedure

This was prepared from R-(−)-2-phenylglycinol and cis-1,4-dichloro-2-butene in 58% yield according to the procedures similar to those described in Preparation 1.

Workup

  1. customthose described in Preparation 1

Sources & evidence

ORD record
ord-17d98089c11e4f08901e318a7aa7ad8a
Source dataset
uspto-grants-2001_10
Patent number
US06310061B2

Reaction notes

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