Potassium Permanganate → HCID 69410961, compound

HRID 382321Notes

Reaction equation

HRID 382321 reaction equation
[Mn]([O-])(=O)(=O)=[O:2].[K+].[CH:7]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH:15]=[C:14]([CH2:17][CH2:18][NH:19][C:20](=[O:22])[CH3:21])[C:13]=2[CH:23]=1)=[O:8]>CC(C)=O.O.CC(C)=O>[C:20]([NH:19][CH2:18][CH2:17][C:14]1[C:13]2[CH:23]=[C:9]([C:7]([OH:2])=[O:8])[CH:10]=[CH:11][C:12]=2[O:16][CH:15]=1)(=[O:22])[CH3:21]

Participants

5

Reactant 2

HCID 516875Potassium PermanganateHCID 18360675HCID 18360675, compound

Product 1

HCID 69410961HCID 69410961, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 18366337Propan-2-one--water (1/1)Solvent

Procedure

2.7 g of potassium permanganate in 50 ml of an acetone/water mixture (50/50) are added at room temperature to a solution of 6.88 mmol of the product obtained in Step D in 30 ml of acetone. The solution is stirred for 2 hours at room temperature and then filtered. The filtrate is concentrated under reduced pressure and chromatographed over silica gel to yield the title product.

Workup

  1. filtrationfiltered
  2. concentrationThe filtrate is concentrated under reduced pressure
  3. customchromatographed over silica gel

Sources & evidence

ORD record
ord-dce7ec2731dd4f9584fcf8e877893787
Source dataset
uspto-grants-2001_10
Patent number
US06310074B1

Reaction notes

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