Benzoyl chloride → HCID 18360261, compound

Participants

Reaction Steps

An amidation reaction and post-treatment were carried out according to the conditions of Example 1, using 1.52 g (7 mmol) of 4-amino-1-benzyl-5-imidazolecarboxamide prepared in Reference Example 2 and 4-methoxy benzoyl chloride separately prepared according to a conventional method, instead of benzoyl chloride, to obtain a crude amide product. The crude amide product was purified by suspension in hot methanol to obtain 1.31 g of 4-(4-methoxybenzoylamino)-1-benzyl-5-imidazolecarboxamide (yield 53%).

Provenance & Evidence