HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4-Amino-1-(3,4,5-trimethoxybenzyl)-5-imidazole carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| Reactant | 4-Benzylideneamino-5-imidazolecarboxamide | HCID 53970446 | — |
| Product | 4-Amino-1-(3,4,5-trimethoxybenzyl)-5-imidazole carboxamide | HCID 18360332 | 73% |
Reaction Steps
1.65 g (7.7 mmol) of 4-benzylideneamino-5-imidazole carboxamide, 4.26 g (30.8 mmol) of potassium carbonate, and 3.84 g (23 mmol) of 3,4,5-trimethoxybenzyl chloride were reacted in the same manner as in Reference Example 2 to obtain 1.7 g of 4-amino-1-(3,4,5-trimethoxybenzyl)-5-imidazole carboxamide (yield 73%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310070B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-9257c191563c4265ae7706703b1553b6 |
| Source note | uspto-grants-2001_10 |