HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → HCID 18360600, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 3-Fluorobenzoyl chloride | HCID 74376 | — |
| Reactant | 1-benzyl-4-amino-1H-imidazole-5-carboxamide | HCID 14000620 | — |
| Product | HCID 18360600 | HCID 18360600 | 78% |
Reaction Steps
An amidation reaction and post-treatment were carried out under the same conditions as in Example 1, using 2.16 g (9.99 mmol) of 4-amino-1-benzyl-5-imidazolecarboxamide which was prepared in the same manner as in Reference Example 2 and 3-fluorobenzoyl chloride, instead of benzoyl chloride, to obtain 2.63 g of 1-benzyl-4-(3-fluorobenzoylamino)-5-imidazolecarboxamide (yield 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310070B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-2149406267cc459ba8c11a0771ecf467 |
| Source note | uspto-grants-2001_10 |