Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- → HCID 18360475, compound

Participants

Reaction Steps

An amidation reaction and post-treatment were carried out following the conditions of Example 17, using 1.13 g (4.50 mmol) of 4-amino-1-(3-chlorobenzyl)-5-imidazolecarboxamide prepared in the same manner as in Example 51 and 2-(N-t-butyloxycarbonyl-N-methylamino)acetic acid instead of 3-pyridylacetic acid hydrochloride to obtain 1.61 g of 4-(2-(N-t-butyloxycarbonyl-N-methylamino)acetylamino)-1-(3-chlorobenzyl)-5-imidazolecarboxamide (yield 85%).

Provenance & Evidence