Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- → HCID 18360544, compound

Participants

Reaction Steps

An amidation reaction and post-treatment were carried out following the conditions of Example 17, using 2.00 g (8.54 mmol) of 4-amino-1-(2-fluorobenzyl)-5-imidazolecarboxamide prepared in the same manner as in Example 113 and 2-(N-t-butyloxycarbonyl-N-methylamino)acetic acid instead of 3-pyridylacetic acid hydrochloride to obtain 3.35 g of 4-(2-(N-t-butyloxycarbonyl-N-methylamino)acetylamino)-1-(2-fluorobenzyl)-5-imidazolecarboxamide (yield 97%).

Provenance & Evidence