反应详情

The 5-acetyloxindole (54 g, 308 mmol), acetic acid (400 ml) and palladium on carbon (10%, 5 g) are combined and treated with hydrogen for 14 hours at 55 psi. The catalyst is removed by filtering through a bed of Celite, the filtrate is concentrated under reduced pressure and the residue is treated with ether to give 5-ethyloxindole

1. customThe catalyst is removed
2. filtrationby filtering through a bed of Celite
3. concentrationthe filtrate is concentrated under reduced pressure
4. additionthe residue is treated with ether