HuagongsheHuagongshe Chemistry Print Report · For research reference only
Oxalic Acid → (E)-2-Styryl-1-(4-trifloromethyl-2-Pyrimidyl)-1H-benzimidazole oxalate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Oxalic Acid | HCID 971 | — |
| Reactant | 2-(2-Phenylethenyl)-1h-benzimidazole | HCID 242965 | — |
| Reactant | 2-Chloro-4-(trifluoromethyl)pyrimidine | HCID 2773912 | — |
| Reactant | (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole | HCID 9796241 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (E)-2-Styryl-1-(4-trifloromethyl-2-Pyrimidyl)-1H-benzimidazole oxalate | HCID 22736656 | — |
Reaction Steps
Free base of the titled compound was prepared from 2-styryl-1H-benzimidazole and 2-chloro-4-trifluromethyl-pyrimidine according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method B). The free base and oxalic acid were dissolved into ethyl acetate. Concentration and recrystallization from ethyl acetate/n-hexane yielded the titled compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310079B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-dab6d3451924418dbc26f907c2f725a7 |
| Source note | uspto-grants-2001_10 |