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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382554Generated: October 26, 2026

4-Fluoro-2-nitroaniline → (E)-5-Fluoro-1-(2-pyridyl)-2-styryl-1H-benzimidazole

https://huagongshe.com/reaction/382554

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluoro-2-nitroanilineHCID 67769—
Reactant(E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazoleHCID 22736704—
Product(E)-5-Fluoro-1-(2-pyridyl)-2-styryl-1H-benzimidazoleHCID 22736771—

Reaction Steps

The titled compound was prepared from 4-fluoro-2-nitroaniline according to the preparation of (E)-1-(2-pyridyl)-2-styryl-5-trifluoromethyl-1H-benzimidazole (Example 57).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310079B1
Source datasetuspto-grants-2001_10
ORD IDord-2e2309b29de240a3804c6e495991c029
Source noteuspto-grants-2001_10