Acetyl chloride → 2-Methyl-2-(2-pyridyl)-1H-benzimidazole

HRID 382591Notes

Reaction equation

HRID 382591 reaction equation
CO[C:3]1[CH:15]=[CH:14][C:6]([NH:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10]N=2)=[C:5]([NH2:16])[CH:4]=1.[C:17](Cl)(=O)C.[N:21]1C=CC=C[C:22]=1N1C2C=CC=CC=2N=C1/C=C/C1C=CC=CC=1>>[CH3:17][C:8]1([C:13]2[CH:12]=[CH:11][CH:10]=[CH:22][N:21]=2)[NH:7][C:6]2[CH:14]=[CH:15][CH:3]=[CH:4][C:5]=2[NH:16]1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 9796241(E)-1-(2-pyridyl)-2-styryl-1H-benzimidazoleHCID 227366532-amino-4-methoxy-N-(2-pyridyl)aniline

Product 1

HCID 699109232-Methyl-2-(2-pyridyl)-1H-benzimidazole

Procedure

The titled compound was prepared from 4-methoxy -2-amino-N-(2-pyridyl)aniline and acetyl chloride according to the preparation of (E)-1-(2-pyridyl)-2-styryl-1H-benzimidazole (Example 1, method A).

Sources & evidence

ORD record
ord-98599873b9914756a342721bf7889e7a
Source dataset
uspto-grants-2001_10
Patent number
US06310079B1

Reaction notes

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