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HRID382614

反应详情

EQUATION

反应方程式

HRID 382614 的结构方程式

REACTANTS

反应物

2
结构：CI
HCID6328

Methyl iodide

CH3I

结构：C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3csc4cncn34)[C@H](C)[C@H]12
HCID131722901

未命名化合物

PRODUCTS

生成物

1
结构：C[C@@H](O)[C@H]1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=C(c3csc4cn(C)c[n+]34)[C@H](C)[C@H]12.[I-]
HCID178462280

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

To a suspension of 102 mg of 4-nitrobenzyl (1S,5R,6S)-6-((1R)-1-hydroxyethyl)-2-(imidazo[5,1-b]thiazol-3-yl)-1-methyl-1-carbapen-2-em-3-carboxylate 1.5 ml of dry dichloromethane was added 2.7 ml of iodomethane, and the mixture was stirred under the atmosphere of argon in the darkness at room temperature for 3 days. Unreacted reagent was removed under reduced pressure to give 122 mg of 4-nitrobenzyl (1S,5R,6S)-6-((1R)-1-hydroxyethyl)-1-methyl-2-(6-methylimidazo[5,1-b]thiazolium-3-yl)-1-carbapen-2-em-3-carboxylate iodide.

WORKUP

后处理

  1. customwas removed under reduced pressure