Phenylacetyl chloride → [4-Chloro-2-[[3-methyl-4-(phenylacetyl)-1-piperazinyl]methyl]phenoxy]acetic Acid

HRID 38268Notes

Reaction equation

HRID 38268 reaction equation
[Cl:1][C:2]1[CH:12]=[CH:11][C:5]([O:6][CH2:7][C:8]([OH:10])=[O:9])=[C:4]([CH2:13][N:14]2[CH2:19][CH2:18][N:17](S(CC3C=CC=CC=3)(=O)=O)[CH:16]([CH3:30])[CH2:15]2)[CH:3]=1.[C:31]1([CH2:37][C:38](Cl)=[O:39])[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[Cl:1][C:2]1[CH:12]=[CH:11][C:5]([O:6][CH2:7][C:8]([OH:10])=[O:9])=[C:4]([CH2:13][N:14]2[CH2:19][CH2:18][N:17]([C:38](=[O:39])[CH2:37][C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[CH:16]([CH3:30])[CH2:15]2)[CH:3]=1

Participants

3

Procedure

Prepared by the method of example 30, using the product from example 56 part (a) and benzeneacetyl chloride to give the title compound.

Workup

  1. customPrepared by the method of example 30

Sources & evidence

ORD record
ord-3a5fef43c3064f2ca8a85491525cb85d
Source dataset
uspto-grants-2013_09
Patent number
US08524715B2

Reaction notes

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