Benzoyl chloride → [2-[(4-Benzoyl-3-methyl-1-piperazinyl)methyl]-4-chlorophenoxy]acetic Acid
Reaction equation
[Cl:1][C:2]1[CH:12]=[CH:11][C:5]([O:6][CH2:7][C:8]([OH:10])=[O:9])=[C:4]([CH2:13][N:14]2[CH2:19][CH2:18][N:17](S(CC3C=CC=CC=3)(=O)=O)[CH:16]([CH3:30])[CH2:15]2)[CH:3]=1.[C:31](Cl)(=[O:38])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[C:31]([N:17]1[CH2:18][CH2:19][N:14]([CH2:13][C:4]2[CH:3]=[C:2]([Cl:1])[CH:12]=[CH:11][C:5]=2[O:6][CH2:7][C:8]([OH:10])=[O:9])[CH2:15][CH:16]1[CH3:30])(=[O:38])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1Participants
3
Procedure
Prepared by the method of example 30, using the product from example 56 part (a) and benzoyl chloride to give the title compound.
Workup
- customPrepared by the method of example 30
Sources & evidence
- ORD record
- ord-a895ca551fd749898c5b361b4cf50be3
- Source dataset
- uspto-grants-2013_09
- Patent number
- US08524715B2
Reaction notes
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