Ammonia → HCID 70032616, compound

HRID 382736Notes

Reaction equation

HRID 382736 reaction equation
[C:1]([CH2:6][C:7]([O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:8])(=O)[CH2:2][CH2:3][CH3:4].[NH3:17]>>[NH2:17][C:1]([CH2:2][CH2:3][CH3:4])=[CH:6][C:7]([O:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:8]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 12425358HCID 12425358, compound

Product 1

HCID 70032616HCID 70032616, compound

Procedure

A mixture of benzyl butyrylacetate (22.0 g, 0.10 mol) and 10 g of 4 Å molecular sieves was treated with ammonia gas which was bubbled through the mixture for 38 hrs at 50° C. After filtration, benzyl 3-amino-2-hexenoate was obtained as a yellowish oil (21 g, 95%).

Workup

  1. customwas bubbled through the mixture for 38 hrs at 50° C
  2. filtrationAfter filtration

Sources & evidence

ORD record
ord-152aac04728d416cb35680659b4ba2d3
Source dataset
uspto-grants-2001_10
Patent number
US06310076B1

Reaction notes

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