HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(4-Methylphenoxy)piperidine → 4-[2-(4-p-Tolyloxy-piperidin-1-yl)-ethanesulfonyl]-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(4-Methylphenoxy)piperidine | HCID 3837497 | — |
| Reactant | 4-(2-Chloro-ethanesulfonyl)-phenol | HCID 9813249 | — |
| Product | 4-[2-(4-p-Tolyloxy-piperidin-1-yl)-ethanesulfonyl]-phenol | HCID 9842587 | 59% |
Reaction Steps
The title compound was prepared from 4-(2-chloro-ethanesulfonyl)-phenol and 4-p-tolyloxy-piperidine (prepared according to J. Med. Chem., 1978, 21, 309) in 59% yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310213B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-58cfce06e89b482a8455df997ba41a8f |
| Source note | uspto-grants-2001_10 |