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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 382782Generated: October 26, 2026

4-(2-Chloro-ethanesulfonyl)-phenol → (3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenol

https://huagongshe.com/reaction/382782

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Chloro-ethanesulfonyl)-phenolHCID 9813249—
Reactant(3S,4S)-4-benzylpiperidin-3-olHCID 9899064—
Product(3S,4S)-4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenolHCID 988596366%

Reaction Steps

The title compound was prepared from 4-(2-chloro-ethanesulfonyl)-phenol and (3S,4S)-4-benzyl-piperidine-3-ol in 66% yield as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06310213B1
Source datasetuspto-grants-2001_10
ORD IDord-c91a9fc152084e0d997e615e36a8c9c6
Source noteuspto-grants-2001_10