HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Chloro-ethanesulfonyl)-phenol → (3SR,4SR)-1-[2-(4-Hydroxy-benzenesulfonyl)-ethyl]-4-(4-methyl-benzyl)-piperidin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Chloro-ethanesulfonyl)-phenol | HCID 9813249 | — |
| Reactant | (3SR,4SR)-4-(4-methyl-benzyl)-piperidin-3-ol | HCID 18362020 | — |
| Product | (3SR,4SR)-1-[2-(4-Hydroxy-benzenesulfonyl)-ethyl]-4-(4-methyl-benzyl)-piperidin-3-ol | HCID 9908392 | 30% |
Reaction Steps
The title compound was prepared from 4-(2-chloro-ethanesulfonyl)-phenol and (3SR,4SR)-4-(4-methyl-benzyl)-piperidin-3-ol in 30% yield as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310213B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-59dd963c7d6c4a47b62d8d9b528cc49c |
| Source note | uspto-grants-2001_10 |