Diethyl Ether → HCID 86757541, compound

Participants

Reaction Steps

6 mg (0.05 mmol) of fumaric acid 10 ml of hexane and 10 ml of diethyl ether were added while stirring to a solution of 15 mg (0.05 mmol) of cis-7-ethyl-6,8-dimethoxy-2-methyl-1,2,3,3a,4,9b-hexahydro-benzo[e]isoindol-5-one in 0.1 ml of ethanol. The mixture was stirred at room temperature for a further 2 hours and the solid was subsequently filtered off. 15 mg (75%) of cis-7-ethyl-6,8-dimethoxy-2-methyl-1,2,3,3a, 4,9b-hexahydro-benzo[e]isoindol-5-one fumarate (1:1) were obtained as a beige solid with m.p. 148°.

Provenance & Evidence