Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium borohydride → [4-chloro-2-(hydroxymethyl)phenoxy]-acetic Acid, 1,1-dimethylethyl Ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | Tert-butyl 2-(4-chloro-2-formylphenoxy)acetate | HCID 51357407 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | [4-chloro-2-(hydroxymethyl)phenoxy]-acetic Acid, 1,1-dimethylethyl Ester | HCID 86631069 | 94.5% |
반응 단계
To a solution of (4-chloro-2-formylphenoxy)-acetic acid, 1,1-dimethylethyl ester (2.1 g) in ethanol (20 ml) was added sodium borohydride (0.29 g). After stirring for 10 minutes the reaction was concentrated in vacuo and water added to the residue. The organics were extracted into ethylacetate, washed with brine, dried (MgSO4) and concentrated in vacuo to give the subtitle compound as an oil (2 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08524715B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-0e1c971ff38d4c77a5661f9306b08c84 |
| 출처 메모 | uspto-grants-2013_09 |