Triethylamine → [4-chloro-2-[[(methylsulfonyl)oxy]methyl]phenoxy]-acetic Acid, 1,1-dimethylethyl Ester

Participants

Reaction Steps

A solution of the product of part (d) (1 g) and triethylamine (0.51 ml) in dichloromethane (10 ml) was cooled to 0° C. Methanesulfonyl chloride (0.29 ml) was then added dropwise and the reaction was allowed to reach room temperature. After stirring for 3 hours the reaction was diluted with dichloromethane, washed with water, NaHCO3 (aq), brine, dried (MgSO4) and concentrated in vacuo to give the subtitle compound as an oil (1.13 g).

Provenance & Evidence