3-Formyl-4-hydroxybenzonitrile → (4-Cyano-2-formylphenoxy)acetic Acid, 1,1-dimethylethyl Ester
Reaction equation
Cl[C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])=[C:4]([CH2:17][OH:18])[CH:3]=1.C(C1C=C(C=CC=1O)[C:24]#[N:25])=O>>[C:24]([C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][C:8]([O:10][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:9])=[C:4]([CH:17]=[O:18])[CH:3]=1)#[N:25]Participants
3
Procedure
Prepared by the method of example 1 part (d) using 3-formyl-4-hydroxy-benzonitrile to give the title compound (1.4 g).
Sources & evidence
- ORD record
- ord-c87306a785d94a7a909fc0ad89068f05
- Source dataset
- uspto-grants-2013_09
- Patent number
- US08524715B2
Reaction notes
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