HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pentafluoropyridine → 2-(4-Benzyloxycarbonylphenoxy)-3,4,5,6-tetrafluoropyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pentafluoropyridine | HCID 69690 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Reactant | Potassium 4-benzyloxycarbonylphenoxide | HCID 23672351 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(4-Benzyloxycarbonylphenoxy)-3,4,5,6-tetrafluoropyridine | HCID 18459337 | — |
Reaction Conditions
| Temperature | 0 °C |
|---|
Reaction Steps
33.8 g of pentafluoropyridine (0.2 mol) are dissolved in 500 ml of dimethylformamide, the solution is cooled to 0° C. by means of a cryostat, and a solution of 53.3 g of potassium 4-benzyloxycarbonylphenoxide (0.2 mol) in 400 ml of dimethylformamide is then added drop wise over the course of 2 hours. After 24 hours at 0° C., the potassium salt has reacted.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06310238B1 |
| Source dataset | uspto-grants-2001_10 |
| ORD ID | ord-7b2db4be0f5d4ad3bc58d67ffe2a1eff |
| Source note | uspto-grants-2001_10 |