1-Acetoxy-2-bromoethane → HCID 86754864, compound

HRID 383045Notes

Reaction equation

HRID 383045 reaction equation
[CH3:1][C:2]1([CH3:29])[O:6][CH:5]([C:7]([NH:9][C:10]2[C:11]([I:28])=[C:12]([CH2:23][O:24][C:25](=[O:27])[CH3:26])[C:13]([I:22])=[C:14]([CH2:17][O:18][C:19](=[O:21])[CH3:20])[C:15]=2[I:16])=[O:8])[CH2:4][O:3]1.[C:30]([O:33][CH2:34][CH2:35]Br)(=[O:32])[CH3:31]>>[C:30]([O:33][CH2:34][CH2:35][N:9]([C:10]1[C:11]([I:28])=[C:12]([CH2:23][O:24][C:25](=[O:27])[CH3:26])[C:13]([I:22])=[C:14]([CH2:17][O:18][C:19](=[O:21])[CH3:20])[C:15]=1[I:16])[C:7]([CH:5]1[CH2:4][O:3][C:2]([CH3:29])([CH3:1])[O:6]1)=[O:8])(=[O:32])[CH3:31]

Participants

3

Reactant 2

HCID 135641-Acetoxy-2-bromoethaneHCID 86754865HCID 86754865, compound

Product 1

HCID 86754864HCID 86754864, compound

Procedure

5-(2,2,-Dimethyl-1,3-dioxolane-4-carbamido)-2,4,6-triiodo-1,3-di-(acetoxymethyl) benzene was alkylated with 2-bromoethyl acetate according to Example 30a. The crude product, containing some O-alkylated material was used directly in next step.

Sources & evidence

ORD record
ord-0f72f5e3a9c8415f92d4467dbb47e373
Source dataset
uspto-grants-2001_10
Patent number
US06310243B1

Reaction notes

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