Sodium Hydroxide → HCID 9918386, compound

HRID 383060Notes

Reaction equation

HRID 383060 reaction equation
C([O:4][CH:5]([CH:37]([O:43]C(=O)C)[CH2:38][O:39]C(=O)C)[C:6]([NH:8][C:9]1[C:10]([I:36])=[C:11]([CH2:31][O:32]C(=O)C)[C:12]([I:30])=[C:13]([C:28]=1[I:29])[C:14]([NH:16][CH2:17][CH:18]([O:24]C(=O)C)[CH2:19][O:20]C(=O)C)=[O:15])=[O:7])(=O)C.[OH-].[Na+]>>[OH:4][CH:5]([CH:37]([OH:43])[CH2:38][OH:39])[C:6]([NH:8][C:9]1[C:10]([I:36])=[C:11]([CH2:31][OH:32])[C:12]([I:30])=[C:13]([C:28]=1[I:29])[C:14]([NH:16][CH2:17][CH:18]([OH:24])[CH2:19][OH:20])=[O:15])=[O:7]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 18429174HCID 18429174, compound

Product 1

HCID 9918386HCID 9918386, compound

Procedure

5-[N′-(2,3,4-Triacetoxybutanoyl)amino]-3-acetoxymethyl-N-(2,3-diacetoxypropyl)-2,4,6-triiodobenzamide (13.8 g, 14.0 mmol) was hydrolysed using sodium hydroxide (4.0 g, 0.10 mol) according to the procedure given in Example 79c. The product was isolated in 68% yield after purification.

Workup

  1. customThe product was isolated in 68% yield
  2. customafter purification

Sources & evidence

ORD record
ord-a7440c3fa05b4d50bb016098ec75ee14
Source dataset
uspto-grants-2001_10
Patent number
US06310243B1

Reaction notes

Loading…