1-Bromo-4-nitrobenzene → 3'-Methyl[1,1'-biphenyl]-4-amine

HRID 383068Notes

Reaction equation

Br[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][CH:3]=1.Br[C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[CH:13]=1>>[NH2:8][C:5]1[CH:6]=[CH:7][C:2]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([CH3:18])[CH:13]=2)=[CH:3][CH:4]=1

Participants

Reactant 2

HCID 114661-Bromo-4-nitrobenzene

HCID 115603-Bromotoluene

Product 1

HCID 27598253'-Methyl[1,1'-biphenyl]-4-amine

Procedure

The title compound was prepared by Suzuki coupling of 1-bromo-4-nitrobenzene and 1-bromo-3-methylbenzene.

Sources & evidence

ORD record: ord-5f6aa9cbab0a44e7b1de00c89c5c4583
Source dataset: uspto-grants-2001_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06310095B1

Reaction notes

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