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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 38307Generated: October 25, 2026

3-(2-Oxo-1,3-oxazolidin-3-yl)benzaldehyde → 4-hydroxy-3-[3-[3-(2-oxo-oxazolidin-3-yl)phenyl]-1-oxo-2-propenyl]-6-methyl-2(1H)-pyridinone

https://huagongshe.com/reaction/38307

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Oxo-1,3-oxazolidin-3-yl)benzaldehydeHCID 23131824—
Reactant2(1H)-Pyridinone, 3-acetyl-4-hydroxy-6-methyl-HCID 54676154—
Product4-hydroxy-3-[3-[3-(2-oxo-oxazolidin-3-yl)phenyl]-1-oxo-2-propenyl]-6-methyl-2(1H)-pyridinoneHCID 13636734541.2%

Reaction Steps

According to the same manner as that of Example 16 except that 0.33 g of 3-acetyl-4-hydroxy-6-methyl-2(1H)-pyridinone was used in place of 3-acetyl-4-hydroxy-1,6-dimethyl-2(1H)-pyridinone, and 0.30 g of 3-(2-oxo-oxazolidin-3-yl)benzaldehyde was used in place of 3-(methoxycarbonyl)benzaldehyde, 0.22 g of 4-hydroxy-3-[3-[3-(2-oxo-oxazolidin-3-yl)phenyl]-1-oxo-2-propenyl]-6-methyl-2(1H)-pyridinone [Compound No. (3a-37)] was obtained as a yellow crystal.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524729B2
Source datasetuspto-grants-2013_09
ORD IDord-db6e22846ee14d6d9c1754cb94a8324d
Source noteuspto-grants-2013_09