2-(cyclohexylmethoxy)-1H-isoindole-1,3(2H)-dione → N-(Cyclohexylmethyloxy)aminomethylidene-2-(2-methylphenyl)benzoic acid methyl ester

HRID 383155Notes

Reaction equation

HRID 383155 reaction equation
[CH:1]1([CH2:7][O:8][N:9]2C(=O)C3=CC=CC=C3[C:10]2=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:20][O:21][C:22](=[O:38])[C:23]1[CH:28]=[CH:27][C:26](C=O)=[CH:25][C:24]=1[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=1[CH3:37]>>[CH3:20][O:21][C:22](=[O:38])[C:23]1[CH:24]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=2[CH3:37])[C:25](=[CH:10][NH:9][O:8][CH2:7][CH:1]2[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[CH:26]=[CH:27][CH:28]=1

Participants

3

Reactant 2

HCID 140744162-(cyclohexylmethoxy)-1H-isoindole-1,3(2H)-dioneHCID 206491994-Formyl-2-(2-methylphenyl)benzoic acid methyl ester

Product 1

HCID 86757558N-(Cyclohexylmethyloxy)aminomethylidene-2-(2-methylphenyl)benzoic acid methyl ester

Procedure

The desired product was prepared using the method described in Example 1176B starting with the compound from Example 1185A and N-[4-Formyl-2-(2-methylphenyl)benzoic acid methyl ester, prepared using the method of Example 403G and starting with the alcohol prepared in Example 1178C.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-32dbe84571ed4415957a9cfc038f09cb
Source dataset
uspto-grants-2001_10
Patent number
US06310095B1

Reaction notes

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