4-Aminophenol → 4,4'-(Chromeno[6,7-e][1,3]oxazine-3,7(2H,4H,8H)-diyl)diphenol

Participants

Reaction Steps

4′,7-Dihydroxyisoflav-3-ene (509 mg, 2.12 mmol) and 4-aminophenol (307 mg, 2.81 mmol) were dissolved in ethanol (15 ml). Formaldehyde solution (2 ml, 0.03 mol, 37% wt.) was added and the reaction stirred at room temperature for 3 days. The resulting precipitate was collected to afford the title compound (178 mg, 79%).

Provenance & Evidence