Ethanol → HCID 25002238, compound

HRID 383235Notes

Reaction equation

HRID 383235 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:16]=[CH:17][CH:18]=1)[C:5]1[CH2:6][O:7][C:8]2[C:13]([CH:14]=1)=[CH:12][CH:11]=[C:10](O)[CH:9]=2.[NH2:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[CH2:26]=[O:27].[CH2:28](O)C>>[C:20]1([N:19]2[CH2:28][C:11]3[CH:12]=[C:13]4[C:8](=[CH:9][C:10]=3[O:27][CH2:26]2)[O:7][CH2:6][C:5]([C:4]2[CH:3]=[C:2]([OH:1])[CH:18]=[CH:17][CH:16]=2)=[CH:14]4)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

5

Reactant 4

HCID 702EthanolHCID 712FormaldehydeHCID 6115AnilineHCID 9813510HCID 9813510, compound

Product 1

HCID 25002238HCID 25002238, compoundYield 61%

Procedure

3′,7-Dihydroxyisoflav-3-ene (175 mg, 0.73 mmol) was dissolved in ethanol (1 ml). Aniline (0.08 ml, 0.88 mmol) was added followed by formaldehyde solution (0.6 ml, 8.06 mmol, 37% wt.). The reaction was stirred at room temperature for 3 days. The resulting precipitate was collected to afford the title compound (160 mg, 61%).

Workup

  1. customThe resulting precipitate was collected

Sources & evidence

ORD record
ord-be21f0f5f9194ccf80c91dfc153e87d1
Source dataset
uspto-grants-2013_02
Patent number
US08367659B2

Reaction notes

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