HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Cyclopent-1-en-1-yl)boronic acid → (1SR,3SR)-3-[3-(2-Cyclopent-1-enyl-pyridin-4-yl)-imidazo[1,2-a]pyridin-6-ylamino)-cyclohexanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Cyclopent-1-en-1-yl)boronic acid | HCID 3861343 | — |
| Reactant | (1SR,3RS)-3-[3-(2-Chloro-pyridin-4-yl)-imidazo[1,2-a]pyridin-6-ylamino)-cyclohexanol | HCID 86644340 | — |
| Product | (1SR,3SR)-3-[3-(2-Cyclopent-1-enyl-pyridin-4-yl)-imidazo[1,2-a]pyridin-6-ylamino)-cyclohexanol | HCID 68483389 | — |
Reaction Steps
The title compound is prepared from (1SR,3SR)-3-[3-(2-Chloro-pyridin-4-yl)-imidazo[1,2-a]pyridin-6-ylamino)-cyclohexanol (Intermediate Q) and Cyclopent-1-enyl boronic acid using a procedure analogous to that described in Example 2.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367662B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-cb5f88dd82064bbaaafde2070cbcf45d |
| Source note | uspto-grants-2013_02 |