Piperidine → HCID 75288717, compound

Participants

Reaction Steps

To 3-(3-formylpyrazolo[1,5-a]pyrimidin-5-yl)benzoate (40 mg, 0.14 mmol) in 0.5 mL EtOH was added rhodanine (19 mg, 0.14 mmol) and piperidine (14 μL, 0.14 mmol). The mixture was stirred at room temperature overnight for three nights. The solid formed was isolated by filtration and purified by preparative TLC (1% MeOH/DCM) to yield methyl 3-(3-((4-oxo-2-thioxothiazolidin-5-ylidene)methyl)pyrazolo[1,5-a]pyrimidin-5-yl)benzoate. LCMS (M+1=397)

Provenance & Evidence