Thiazolidinedione → HCID 75288718, compound

Participants

Reaction Conditions

Reaction Steps

To 3-(3-formylpyrazolo[1,5-a]pyrimidin-5-yl)benzoate (27 mg, 0.096 mmol) in 0.5 mL EtOH was added 2,4-thiazolidinedione (11 mg, 0.096 mmol) and piperidine (9.5 μL, 0.096 mmol). The mixture was stirred at 50° C. overnight. The solid formed was isolated by filtration and air dried to yield 27 mg methyl 3-(3-((2,4-dioxothiazolidin-5-ylidene)methyl)pyrazolo[1,5-a]pyrimidin-5-yl)benzoate as an orange solid (74% yield). LCMS (M+1=381)

Provenance & Evidence