Sodium Hydroxide → HCID 75288719, compound

Participants

Reaction Steps

To methyl 3-(3-((2,4-dioxothiazolidin-5-ylidene)methyl)pyrazolo[1,5-a]pyrimidin-5-yl)benzoate (25 mg, 0.066 mmol) in EtOH was added 1 mL of 6M NaOH. The mixture was stirred at room temperature overnight. Solvent was removed under reduced pressure. Water was added and the mixture was neutralized with 1M HCl. The resulting solid was isolated by filtration and air dried to yield 3-(3-((2,4-dioxothiazolidin-5-ylidene)methyl)pyrazolo[1,5-a]pyrimidin-5-yl)benzoic acid. LCMS (M+1=367)

Provenance & Evidence