Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Hydantoin | HCID 10006 | — |
| Reactant | 5-(3-Tert-butylphenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde | HCID 58196689 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178440914 | HCID 178440914 | — |
Reaction Steps
To 5-(3-tert-butylphenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde (39 mg, 0.133 mmol) in EtOH was added hydantoin (28 mg, 0.280 mmol) and piperidine (13 μL, 0.133 mmol). The mixture was heated at 70° C. overnight. The solid formed was isolated by filtration and air dried to yield 5-((5-(3-tert-butylphenylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methylene)imidazolidine-2,4-dione. LCMS (M+1=377)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08367681B2 |
|---|
| Source dataset | uspto-grants-2013_02 |
|---|
| ORD ID | ord-db230e3bea1a4f05b6e035119b40e325 |
|---|
| Source note | uspto-grants-2013_02 |
|---|
