HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 383664Generated: October 26, 2026
Thiazolidinedione → HCID 178440914, compound
https://huagongshe.com/reaction/383664
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thiazolidinedione | HCID 5437 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 5-(3-Tert-butylphenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde | HCID 58196689 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178440914 | HCID 178440914 | — |
Reaction Steps
To 5-(3-tert-butylphenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde (39 mg, 0.133 mmol) in EtOH was added 2,4-thiazolidinedione (16 mg, 0.133 mmol) and piperidine (13 μL, 0.133 mmol). The mixture was heated at 70° C. The solid formed was isolated by filtration and air dried to yield 5-((5-(3-tert-butylphenylamino)pyrazolo[1,5-a]pyrimidin-3-yl)methylene)imidazolidine-2,4-dione. LCMS (M+1=394)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08367681B2 |
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| Source dataset | uspto-grants-2013_02 |
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| ORD ID | ord-aee8f7776001478e9c2beb8532dd7b11 |
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| Source note | uspto-grants-2013_02 |
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