Rhodanine → HCID 75288130, compound

HRID 383691Notes

Reaction equation

HRID 383691 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][N:11]2[N:14]=[CH:15][C:16]([CH:17]=[C:18]3[S:22][C:21](=O)[NH:20][C:19]3=[O:24])=[C:10]2[N:9]=1.[S:25]1CC(=O)NC1=S>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][N:11]2[N:14]=[CH:15][C:16]([CH:17]=[C:18]3[S:22][C:21](=[S:25])[NH:20][C:19]3=[O:24])=[C:10]2[N:9]=1

Participants

3

Reactant 2

HCID 1201546RhodanineHCID 75288131HCID 75288131, compound

Product 1

HCID 75288130HCID 75288130, compound

Procedure

5-((5-(2-Fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)methylene)-2-thioxothiazolidin-4-one was prepared using the same procedure as for the synthesis of 5-((5-(2-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)methylene)thiazolidine-2,4-dione using Rhodanine instead of thiazolidine-2,4-dione.

Sources & evidence

ORD record
ord-8704e6da6b15414ca307b6991e4228ac
Source dataset
uspto-grants-2013_02
Patent number
US08367681B2

Reaction notes

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