Hydantoin → HCID 68660069, compound

HRID 383692Notes

Reaction equation

[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][N:11]2[N:14]=[CH:15][C:16]([CH:17]=[C:18]3S[C:21](=[O:23])[NH:20][C:19]3=[O:24])=[C:10]2[N:9]=1.[NH:25]1CC(=O)NC1=O>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][N:11]2[N:14]=[CH:15][C:16]([CH:17]=[C:18]3[NH:25][C:21](=[O:23])[NH:20][C:19]3=[O:24])=[C:10]2[N:9]=1

Participants

Reactant 2

HCID 10006Hydantoin

HCID 75288131HCID 75288131, compound

Product 1

HCID 68660069HCID 68660069, compound

Procedure

5-((5-(2-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)methylene)imidazolidine-2,4-dione was prepared using the same procedure as for the synthesis of 5-((5-(2-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)methylene)thiazolidine-2,4-dione using hydantoin instead of thiazolidine-2,4-dione.

Sources & evidence

ORD record: ord-304f7f7763874313b0dbbc1a50b3120a
Source dataset: uspto-grants-2013_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08367681B2

Reaction notes

Loading…