HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 383697Generated: October 30, 2026
4-Isopropoxyaniline → HCID 58196451, compound
https://huagongshe.com/reaction/383697
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Isopropoxyaniline | HCID 82112 | — |
| Reactant | 5-Chloropyrazolo(1,5-a)pyrimidine-3-carbaldehyde | HCID 58196401 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 58196451 | HCID 58196451 | — |
Reaction Steps
To 5-chloropyrazolo[1,5-a]pyrimidine-3-carbaldehyde (30 mg, 0.166 mmol) in dioxane was added 4-isopropoxyaniline (125 mg, 0.829 mmol). The mixture was heated in microwave for 20 minutes at 120° C. The solid formed was isolated by filtration and air dried to yield 5-(4-isopropoxyphenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde with impurities that will be removed in the final step. LCMS (M+1=297)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08367681B2 |
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| Source dataset | uspto-grants-2013_02 |
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| ORD ID | ord-ad40d607811a4c75ac4572b855c55b52 |
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| Source note | uspto-grants-2013_02 |
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