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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 383697Generated: October 30, 2026

4-Isopropoxyaniline → HCID 58196451, compound

https://huagongshe.com/reaction/383697

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-IsopropoxyanilineHCID 82112—
Reactant5-Chloropyrazolo(1,5-a)pyrimidine-3-carbaldehydeHCID 58196401—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 58196451HCID 58196451—

Reaction Conditions

Temperature120 °C

Reaction Steps

To 5-chloropyrazolo[1,5-a]pyrimidine-3-carbaldehyde (30 mg, 0.166 mmol) in dioxane was added 4-isopropoxyaniline (125 mg, 0.829 mmol). The mixture was heated in microwave for 20 minutes at 120° C. The solid formed was isolated by filtration and air dried to yield 5-(4-isopropoxyphenylamino)pyrazolo[1,5-a]pyrimidine-3-carbaldehyde with impurities that will be removed in the final step. LCMS (M+1=297)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08367681B2
Source datasetuspto-grants-2013_02
ORD IDord-ad40d607811a4c75ac4572b855c55b52
Source noteuspto-grants-2013_02