HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-chloropropane → HCID 13731112, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-chloropropane | HCID 8006 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Piperazine,1-[4-(4-chlorophenyl)butyl]- | HCID 14097058 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 13731112 | HCID 13731112 | 125.7% |
Reaction Steps
The procedure described in Example 1(a) was followed, using 10.0 g of 4-(4-chlorophenyl)butyl piperazine, 47.2 g of 1-bromo-3-chloropropane, 150 ml of dimethyl sulfoxide and 11.2 g of potassium hydroxide, to give 10.0 g (82% of theory) of 1-[4-(4-chlorophenyl)butyl]-4-(3-chloropropyl)piperazine dihydrochloride as a white crystalline solid, M.p. 266°-268° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04722926 |
| Source dataset | uspto-grants-1988_02 |
| ORD ID | ord-3a99d50f95d64431bf061d9f3353a09f |
| Source note | uspto-grants-1988_02 |