HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azetidine → Azetidin-1-yl(7-(4-benzylpiperazin-1-yl)benzofuran-2-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azetidine | HCID 10422 | — |
| Reactant | 7-(4-Benzyl-piperazin-1-yl)-benzofuran-2-carboxylic acid ethyl ester | HCID 59636745 | — |
| Product | Azetidin-1-yl(7-(4-benzylpiperazin-1-yl)benzofuran-2-yl)methanone | HCID 59636710 | — |
Reaction Steps
The compound was prepared according to the procedure disclosed in Example 39c starting from ethyl 7-(4-benzylpiperazin-1-yl)benzofuran-2-carboxylate (1.0 g, 2.74 mmol) (Example 39b) and azetidine (0.20 mL, 3.02 mmol). Yield: 0.52 g (51%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367676B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-bb7a6692190b4e0a8be926f7b682478f |
| Source note | uspto-grants-2013_02 |