HCID 59636708, compound → HCID 59636722, compound

HRID 383841Notes

Reaction equation

HRID 383841 reaction equation
[CH3:1][N:2]([CH3:20])[C:3]([C:5]1[O:6][C:7]2[C:13]([N:14]3[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]3)=[CH:12][CH:11]=[CH:10][C:8]=2[CH:9]=1)=[O:4].CC1C=CC(S(O[CH2:32][CH2:33][C:34]2[C:39]([O:40][CH3:41])=[CH:38][CH:37]=[CH:36][N:35]=2)(=O)=O)=CC=1>>[CH3:41][O:40][C:39]1[C:34]([CH2:33][CH2:32][N:17]2[CH2:18][CH2:19][N:14]([C:13]3[C:7]4[O:6][C:5]([C:3]([N:2]([CH3:20])[CH3:1])=[O:4])=[CH:9][C:8]=4[CH:10]=[CH:11][CH:12]=3)[CH2:15][CH2:16]2)=[N:35][CH:36]=[CH:37][CH:38]=1

Participants

3

Reactant 2

HCID 59636708HCID 59636708, compoundHCID 59636743N,N-dimethyl-7-(piperazin-1-yl)benzofuran-2-carboxamide

Product 1

HCID 59636722HCID 59636722, compound

Procedure

The compound was prepared according to the procedure disclosed in Example 46 starting from N,N-dimethyl-7-(piperazin-1-yl)benzofuran-2-carboxamide (0.085 g, 0.31 mmol) (Example 39d) and 2-(3-methoxypyridin-2-yl)ethyl 4-methylbenzenesulfonate (0.092 g, 0.31 mmol). The product was purified by preparative HPLC to give the title compound.

Workup

  1. customThe compound was prepared
  2. customThe product was purified by preparative HPLC

Sources & evidence

ORD record
ord-14240f282f34471f8cb10ea3ca1936a3
Source dataset
uspto-grants-2013_02
Patent number
US08367676B2

Reaction notes

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