1-methyl-1H-imidazole-4-sulfonyl chloride → HCID 68631474, compound

HRID 383894Notes

Reaction equation

HRID 383894 reaction equation
[C:1]1([C:7]2([C:13]([O:15][CH3:16])=[O:14])[CH2:12][CH2:11][CH2:10][NH:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:17][N:18]1[CH:22]=[C:21]([S:23](Cl)(=[O:25])=[O:24])[N:20]=[CH:19]1>>[CH3:17][N:18]1[CH:22]=[C:21]([S:23]([N:9]2[CH2:10][CH2:11][CH2:12][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)([C:13]([O:15][CH3:16])=[O:14])[CH2:8]2)(=[O:25])=[O:24])[N:20]=[CH:19]1

Participants

3

Reactant 2

HCID 27368871-methyl-1H-imidazole-4-sulfonyl chlorideHCID 68427351HCID 68427351, compound

Product 1

HCID 68631474HCID 68631474, compound

Procedure

The target was synthesized as in Production Example 1(1), using the raw material methyl 3-phenylpiperidine-3-carboxylate described in literature (Tetrahedron Letters 42 (2001) 1645-1646) and 1-methyl-1H-imidazole-4-sulfonyl chloride.

Workup

  1. customThe target was synthesized as in Production Example 1(1)

Sources & evidence

ORD record
ord-8af61adf79084bf8b09fd781f2f08d24
Source dataset
uspto-grants-2013_02
Patent number
US08367698B2

Reaction notes

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