HCID 59233323, compound → HCID 68560894, compound

HRID 383899Notes

Reaction equation

HRID 383899 reaction equation
[CH3:1][C:2]1([CH3:28])[C:11](=O)[C:10]([CH3:14])([CH3:13])[C:9]2[C:4](=[C:5]3[CH2:27][CH2:26][CH2:25][C:6]3=[C:7]([C:15]3[CH:24]=[CH:23][CH:22]=[C:21]4[C:16]=3[CH:17]=[CH:18][CH:19]=[N:20]4)[CH:8]=2)[NH:3]1.[CH3:29]C1C(C2C=C3C(=C4CCCC=24)NC(C)(C)C(=C)C3(C)C)=C(C)ON=1>>[CH3:1][C:2]1([CH3:28])[C:11](=[CH2:29])[C:10]([CH3:14])([CH3:13])[C:9]2[C:4](=[C:5]3[CH2:27][CH2:26][CH2:25][C:6]3=[C:7]([C:15]3[CH:24]=[CH:23][CH:22]=[C:21]4[C:16]=3[CH:17]=[CH:18][CH:19]=[N:20]4)[CH:8]=2)[NH:3]1

Participants

3

Reactant 2

HCID 59233323HCID 59233323, compoundHCID 59233373HCID 59233373, compound

Product 1

HCID 68560894HCID 68560894, compoundYield 21%

Procedure

Using 2,2,4,4-tetramethyl-6-(quinolin-5-yl)-2,3,4,7,8,9-hexahydro-1H-cyclopenta[h]quinolin-3-one obtained in Example instead of 6-(3,5-dimethylisoxazol-4-yl)-2,2,4,4-tetramethyl-2,3,4,7,8,9-hexahydro-1H-cyclopenta[h]quinolin-3-one of Example 23 and according to a similar method, the title compound (13 mg, 21%) was obtained.

Sources & evidence

ORD record
ord-ab7f31673cd54afdbef198340fd1c6a8
Source dataset
uspto-grants-2013_02
Patent number
US08367695B2

Reaction notes

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