3,5-Dimethylisoxazole-4-boronic acid pinacol ester → HCID 24962502, compound

Participants

Reaction Steps

Using 3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isoxazole instead of tert-butyl 2,2,4,4-tetramethyl-6-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-2,3,4,7,8,9-hexahydro-1H-cyclopenta[h]quinolin-3-one-1-carboxylate of Example 1, 10), using tert-butyl 4-allyl-6-bromo-2,2,4-trimethyl-2,3,4,7,8,9-hexahydro-1H-cyclopenta[h]quinolin-3-one-1-carboxylate obtained in Example 50, 1) instead of 4-bromo-3-chlorophenol of Example 1, 10) and according to a similar method, the title compound (25 mg, 31%) was obtained.

Provenance & Evidence