Hydrochloric Acid → HCID 59527532, compound

Participants

Reaction Steps

To ethyl 4-[(3-methyl-4-oxo-1,4-dihydroquinolin-2-yl)methoxy]-2-(tetrahydro-2H-pyran-4-ylmethoxy)benzoate (110 mg) were added ethanol (3 mL) and a 0.5M aqueous sodium hydroxide solution (10 mL), and the mixture was stirred at room temperature for 4 hours. The reaction mixture was adjusted to a pH of 7 by adding 1M hydrochloric acid under ice-cooling. The resulting solid was collected by filtration, washed with water, and dried to obtain 4-[(3-methyl-4-oxo-1,4-dihydroquinolin-2-yl)methoxy]-2-(tetrahydro-2H-pyran-4-ylmethoxy)benzoic acid (100 mg).

Provenance & Evidence