HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(1-Methyl-1H-pyrazol-4-yl)spiro[chroman-2,4'-piperidin]-4-one hydrochloride → Methyl 2',6'-diethoxy-4'-{[6-(1-methyl-1H-pyrazol-4-yl)-4-oxospiro[chroman-2,4'-piperidin]-1'-yl]carbonyl}biphenyl-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(1-Methyl-1H-pyrazol-4-yl)spiro[chroman-2,4'-piperidin]-4-one hydrochloride | HCID 66782546 | — |
| Reactant | 2,6-Diethoxy-4'-(methoxycarbonyl)biphenyl-4-carboxylic acid | HCID 67055548 | — |
| Product | Methyl 2',6'-diethoxy-4'-{[6-(1-methyl-1H-pyrazol-4-yl)-4-oxospiro[chroman-2,4'-piperidin]-1'-yl]carbonyl}biphenyl-4-carboxylate | HCID 58208685 | — |
Reaction Steps
In the same manner as in Example 25, the intended compound was obtained as a colorless solid using 6-(1-methyl-1H-pyrazol-4-yl)spiro[chroman-2,4′-piperidin]-4-one hydrochloride and 2,6-diethoxy-4′-(methoxycarbonyl)biphenyl-4-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08524730B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-2b7a8ebb808649f2bc3efd76d413ddec |
| Source note | uspto-grants-2013_09 |