HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → (S)-methyl 2-amino-4,4-difluoro-5-phenylpentanoate hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Methyl (S)-2-benzyloxycarbonylamino-4,4-difluoro-5-phenylpentanoate | HCID 57535357 | — |
| Product | (S)-methyl 2-amino-4,4-difluoro-5-phenylpentanoate hydrobromide | HCID 66939992 | — |
Reaction Steps
A mixture of (S)-methyl 2-(benzyloxycarbonylamino)-4,4-difluoro-5-phenylpentanoate (188 mg, 0.5 mmol) and hydrogen bromide (2 mL) was stirred at RT for two hr, after which the solvent was removed to give the title (S)-methyl 2-amino-4,4-difluoro-5-phenylpentanoate hydrobromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08367732B2 |
| Source dataset | uspto-grants-2013_02 |
| ORD ID | ord-c951b990760a4f349cdf94b6235ce274 |
| Source note | uspto-grants-2013_02 |